Modern histological classification of low grade B-cell lymphomas

The new World Health Organisation (WHO) lymphoma classification identifies individual clinicopathological entities; integrating morphology, immunophenotype, genotype, normal cell counterpart/cell of origin and clinical features. The degree to which these five characteristics contributes to the definition of individual entities differs from one entity to the other. This classification has received worldwide acceptance in the short term it has been available and has become the gold standard in lymphoma diagnosis.