| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10895552 | Biochimica et Biophysica Acta (BBA) - Reviews on Cancer | 2015 | 10 Pages |
Abstract
Targeting the factors that regulate gene transcription is a compelling strategy in cancer therapeutics. Traditionally, these have been considered intractable targets, but recent work has revealed novel strategies for the regulation of transcription factor activity in cancer. This review will highlight some of the emerging concepts and provide examples where agents that target transcription factors are being exploited clinically for cancer therapies.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cancer Research
Authors
Simon J. Johnston, Jason S. Carroll,