| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10899770 | Cancer Letters | 2015 | 6 Pages |
Abstract
Understanding cancer-specific metabolism is important for identifying novel targets for cancer diagnosis and therapy. Induced acetate/acetyl CoA metabolism is a notable feature that is related to fatty acid synthesis supporting tumor growth. In this review, we focused on the recent findings related to cancer acetate/acetyl CoA metabolism. We also introduce [1-11C]acetate positron emission tomography (PET), which is a useful tool to visualize up-regulation of acetate/acetyl CoA metabolism in cancer, and discuss the utility of [1-11C]acetate PET in cancer diagnosis and its application to personalized medicine.
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Authors
Yukie Yoshii, Takako Furukawa, Tsuneo Saga, Yasuhisa Fujibayashi,