| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10899788 | Cancer Letters | 2014 | 6 Pages |
Abstract
The successful therapy of childhood leukemia has been characterized by careful personalized adaptation of therapy by risk stratification. Yet almost all drugs are relatively non-specific. To achieve greater precision in therapy, druggable targets and specific targeting drugs are necessary. Here we review the recent discoveries of cytokine receptors and their signaling components in high risk leukemias and the potential approaches to target them.
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Authors
Shai Izraeli, Chen Shochat, Noa Tal, Ifat Geron,