| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10899820 | Cancer Letters | 2014 | 6 Pages |
Abstract
Bone metastases are a common problem of many malignancies, including myeloma, breast and prostate cancer. The Wnt inhibitor Dickkopf-1 has been shown to be involved in the process of bone lesions by impairing osteoblast activity. This review will focus on the role of Dickkopf-1 as a mediator of malignant bone disease and discuss its potential as a novel therapeutic target.
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Authors
Tilman D. Rachner, Andy Göbel, Peggy Benad-Mehner, Lorenz C. Hofbauer, Martina Rauner,