| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10899968 | Cancer Letters | 2013 | 11 Pages |
Abstract
⺠MiR-503 simultaneously down-regulates expression of FGF2 and VEGFA and inhibits tumor angiogenesis and growth. ⺠MiR-503 expression is dramatically down-regulated in tumors by epigenetic hypermethylation of its promoter/regulatory region. ⺠This study identifies a novel miRNA-based alternative mechanism by which hypoxia increases expression of FGF2 and VEGFA.
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Cancer Research
Authors
Bisheng Zhou, Ruihua Ma, Wenxia Si, Sisi Li, Yan Xu, Xin Tu, Qing Wang,