| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10899993 | Cancer Letters | 2013 | 8 Pages |
Abstract
⺠Antagonist or siRNA against CCK2R blocked G17-induced activation of STAT3 and Akt in gastric cancer cell lines. ⺠G17-increased COX-2 expression and cell proliferation were blocked by CCK2R antago-31 nist and inhibitors of JAK2 and PI3K. ⺠Knockdown of STAT3 expression attenuated G17-induced PI3K/Akt activation, COX-2 expression, and cell proliferation.
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Authors
Wei Xu, Guo-Sheng Chen, Yun Shao, Xiao-Lin Li, Hai-Chen Xu, Hao Zhang, Guo-Qing Zhu, Yi-Chan Zhou, Xiao-Pu He, Wei-Hao Sun,