Article ID Journal Published Year Pages File Type
10900009 Cancer Letters 2013 10 Pages PDF
Abstract
► Doxorubicin encapsulating human serum albumin nanoparticles (HSA + DOX NPs) were fabricated to confirm the benefit of nanoparticles at the treatment of anoikis-resistant breast cancer cells. ► HSA + DOX NPs were more cytotoxic to anoikis-resistant cancer cells than free doxorubicin. ► HSA + DOX NPs delivered more doxorubicin into cells compared to the free doxorubicin by bypassing the drug efflux pump systems of anoikis-resistant cancer cells.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cancer Research
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