Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10900009 | Cancer Letters | 2013 | 10 Pages |
Abstract
⺠Doxorubicin encapsulating human serum albumin nanoparticles (HSA + DOX NPs) were fabricated to confirm the benefit of nanoparticles at the treatment of anoikis-resistant breast cancer cells. ⺠HSA + DOX NPs were more cytotoxic to anoikis-resistant cancer cells than free doxorubicin. ⺠HSA + DOX NPs delivered more doxorubicin into cells compared to the free doxorubicin by bypassing the drug efflux pump systems of anoikis-resistant cancer cells.
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Authors
Hohyeon Lee, Sunyoung Park, Jong Bin Kim, Jungwook Kim, Hyuncheol Kim,