Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10900022 | Cancer Letters | 2013 | 12 Pages |
Abstract
⺠Cancer stem cells (CSCs) are thought to be responsible for post-therapy relapse of cancer. ⺠AC133, a CSC marker, represents a unique target for the treatment of various tumour types. ⺠Aptamers generated against the CD133 protein bind to two separate epitopes. ⺠These aptamers represent the ideal molecule for use as targeted theranostics.
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Authors
Sarah Shigdar, Liang Qiao, Shu-Feng Zhou, Dongxi Xiang, Tao Wang, Yong Li, Lee Yong Lim, Lingxue Kong, Lianhong Li, Wei Duan,