Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10900030 | Cancer Letters | 2012 | 8 Pages |
Abstract
⺠Coated polymeric implants reduce initial burst release and accommodate heat labile compounds. ⺠Coated polymeric implants deliver almost sustained levels of chemopreventives for long duration (months). ⺠Polymeric implants deliver agents directly systemically and circumvents the oral bioavailability issues. ⺠Withaferin A via implants elicits antitumor response and reduce the required total dose versus the traditional routes. ⺠The implant delivery will allow the efficacy assessment of minor plant constituents and synthetic metabolites in vivo.
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Authors
Farrukh Aqil, Jeyaprakash Jeyabalan, Hina Kausar, Shyam S. Bansal, Ram J. Sharma, Inder P. Singh, Manicka V. Vadhanam, Ramesh C. Gupta,