Tumor grafts derived from sarcoma patients retain tumor morphology, viability, and invasion potential and indicate disease outcomes in the chick chorioallantoic membrane model

► Xenotransplanted sarcomas on the CAM retain histological characteristics and functional behavior of the original tumors. ► Xenoraft viability on the CAM is inversely related to patient survival. ► The CAM assay is a potential prognostic and predictive preclinical xenograft model for sarcoma.