| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10900127 | Cancer Letters | 2008 | 7 Pages |
Abstract
Correlations of phenylalanine and phe/tyr with immune activation markers point to a potential role of inflammation and immune activation in the accumulation of phenylalanine. The relationship between oxidative stress marker isoprostane-8 and phenylalanine as well as sTNF-R75 concentrations suggests a link between reactive oxygen species formed during chronic immune activation and inflammation and the decline of PAH activity, which might underlie the increase of phe/tyr (248 words).
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Authors
Gabriele Neurauter, Anna V. Grahmann, Martin Klieber, Alain Zeimet, Maximilian Ledochowski, Barbara Sperner-Unterweger, Dietmar Fuchs,