Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10901905 | Cancer Letters | 2015 | 22 Pages |
Abstract
Metformin and EGFR-TKI have a synergistic effect in the treatment of DM2 NSCLC patients harboring EGFR-activating mutations. Metformin use is associated with improved survival and delayed onset of acquired resistance to EGFR-TKI.
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Authors
Hengyi Chen, Wenxiu Yao, Qian Chu, Rui Han, Yubo Wang, Jianguo Sun, Dong Wang, Yongsheng Wang, Mengshu Cao, Yong He,