| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10903335 | Differentiation | 2011 | 9 Pages |
Abstract
⺠The fastest and easiest method for in vitro pancreatic β-cell production using three different adult stem cells within a week. ⺠Significantly greater amounts of C-peptide and insulin were released from differentiated cells than from undifferentiated cells. ⺠This efficient differentiation method can give expandable and transplantable amounts of insulin-producing cells from adult stem cells for the patients.
Keywords
IPCsNK6 homeobox 1GvHDNgn3EGM-2Nkx6.1hUCB-MSCPdx1Umbilical cord-derived mesenchymal stem cellsSOX17KGFFGF7UCBEBM-2Cx36GCGMSCINSPPyBSAPancreatic and duodenal homeobox 1bovine serum albumininsulinHESimmunohistochemistyIHCDiabetesGraft-versus-host diseaseDifferentiationUmbilical cord bloodDiabetes mellitusendothelial cell growth medium-2Stem cellshuman embryonic stem cellsMouse embryonic stem cellsMesenchymal stem cellshuman umbilical cord blood-derived mesenchymal stem cellsinsulin-producing cellsKeratinocyte growth factorDurationMeSNeurogenin 3Pancreatic polypeptideProtocolWharton's jellyConnexin-36Glucagon
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Authors
Dilli Ram Bhandari, Kwang-Won Seo, Bo Sun, Min-Soo Seo, Hyung-Sik Kim, Yoo-Jin Seo, Jurga Marcin, Nicolas Forraz, Helene Le Roy, Denner Larry, McGuckin Colin, Kyung-Sun Kang,