Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10903744 | Experimental Cell Research | 2016 | 9 Pages |
Abstract
The extracellular matrix in the healthy breast has an important tumor suppressive role, whereas the abnormal ECM in tumors can promote aggressiveness, and has been linked to breast cancer relapse, survival and resistance to chemotherapy. This review article gives an overview of the elements of the ECM which have been linked to prognosis of breast cancers, including changes in ECM protein composition, splicing, and microstructure.
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Authors
Claire Robertson,