Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10903869 | Experimental Cell Research | 2015 | 6 Pages |
Abstract
Our findings indicated that oxaliplatin-increased gap junction-mediated coupling between satellite glial cells in primary cultures of mouse trigeminal ganglia, and carbenoxolone reversed this effect. Hence, it is proposed that increased gap junction-mediated coupling was seen between satellite glial cells in TG. This observation together with our previous data obtained from a behavioral study suggests that this phenomenon might contribute to chemotherapy-induced nociception following oxaliplatin treatment.
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Authors
Jeppe Nørgaard Poulsen, Rebekah Warwick, Meg Duroux, Menachem Hanani, Parisa Gazerani,