Article ID Journal Published Year Pages File Type
10904003 Experimental Cell Research 2014 8 Pages PDF
Abstract

- Newly identified interactions with the FHA and BRCT domains of NBS1 influence subcellular localization of the MRE11 complex.
- The MRE11 complex promotes TOPBP1 recruitment and ATR activation during replication stress.
- The MRE11 complex is a barrier to oncogene-induced tumorigenesis.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cancer Research
Authors
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