Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10904026 | Experimental Cell Research | 2014 | 6 Pages |
Abstract
The miR-92a family, including miR-25, miR-92a-1, miR-92a-2 and miR-363, arises from three different paralog clusters miR-17-92, miR-106a-363, and miR-106b-25 that are highly conservative in the process of evolution, and it was thought as a group of microRNAs (miRNAs) correlated with endothelial cells. Aberrant expression of miR-92a family was detected in multiple cancers, and the disturbance of miR-92a family was related with tumorigenesis and tumor development. In this review, the progress on the relationship between miR-92a family and their target genes and malignant tumors will be summarized.
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Authors
Molin Li, Xingfang Guan, Yuqiang Sun, Jun Mi, Xiaohong Shu, Fang Liu, Chuangang Li,