| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10904191 | Experimental Cell Research | 2014 | 12 Pages |
Abstract
Esomeprazole administration interfered with proton compartmentalization in acidic organelles and induced a significant dose-dependent toxicity. Among the different histotypes, rhabdomyosarcoma, expressing the highest levels of V-ATPase and whose lysosomes are most acidic, was mostly susceptible to ESOM treatment.
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Authors
Francesca Perut, Sofia Avnet, Caterina Fotia, Serena Rubina Baglìo, Manuela Salerno, Shigekuni Hosogi, Katsuyuki Kusuzaki, Nicola Baldini,