Production of reactive oxygen species by withaferin A causes loss of type collagen expression and COX-2 expression through the PI3K/Akt, p38, and JNK pathways in rabbit articular chondrocytes

Article ID	Journal	Published Year	Pages	File Type
10904320	Experimental Cell Research	2013	13 Pages	PDF

Keywords

NAC DCF-DA DIDS N-acetyl-l-cysteine PGE2 COX-2 WFA L-NMMA Jnk ECM 2′,7′-dichlorodihydrofluorescein diacetate c-Jun N-terminal kinase MAPK PI3K/AKT ROS Osteoarthritis withaferin A Cyclooxygenase-2 Phosphatidylinositol 3-kinase Extracellular matrix mitogen-activated protein kinase Prostaglandin E2 Type II collagen Chondrocytes Reactive oxygen species

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Production of reactive oxygen species by withaferin A causes loss of type collagen expression and COX-2 expression through the PI3K/Akt, p38, and JNK pathways in rabbit articular chondrocytes

Authors

Seon-Mi Yu, Song-Ja Kim,