Article ID Journal Published Year Pages File Type
10904350 Experimental Cell Research 2013 11 Pages PDF
Abstract
► High levels of glucose could promote autophagy in podocyte. ► The effect of high levels of glucose was further enhanced by rapamycin. ► The effect of high levels of glucose was inhibited by 3-methyladenine. ► The effect of high levels of glucose was associated with podocyte expression of LC3-2 and beclin-1. ► High levels of glucose promotes podocyte autophagy through the generation of ROS.
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