| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10904373 | Experimental Cell Research | 2013 | 12 Pages |
Abstract
⺠Islet-1 is a dual regulator of cardiac epithelial-to-mesenchymal transition (EMT). ⺠Islet-1 promotes mesenchymal features in epicardial mesothelial cells via myocardin. ⺠Islet-1 is reduced during TGF-β-induced EMT, which inhibits the EMT process. ⺠Mechanistically, Islet-1 is reduced by microRNA-31 and β-catenin during EMT.
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Authors
Hasse Brønnum, Ditte C. Andersen, Mikael Schneider, Anne Yaël Nossent, Solveig B. Nielsen, Søren P. Sheikh,