Article ID Journal Published Year Pages File Type
10904380 Experimental Cell Research 2013 11 Pages PDF
Abstract
► EGFR content is retained in endosomes by E2/S1P. ► E2/S1P-activated EGFR does not translocate to lysosomes. ► E2/S1P induce prolonged activation of Cdc42 that prevents EGFR degradation. ► S1P3 receptor mediates E2/S1P-induced activation of Cdc42.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cancer Research
Authors
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