Article ID Journal Published Year Pages File Type
10904451 Experimental Cell Research 2012 15 Pages PDF
Abstract
► rudhira-depleted endothelial cells show reduced tube formation due to slow and random cell migration. ► Rudhira re-localizes towards the leading edge and promotes cell migration in endothelial and other cell types. ► During cell migration Rudhira regulates Cdc42 activation and recruitment, controls actin reorganization and cell polarity. ► Rudhira is a novel cytoskeletal protein that interacts with microtubules and intermediate filaments.
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