| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10904455 | Experimental Cell Research | 2012 | 11 Pages |
Abstract
⺠12(S)-LOX is up-regulated in inflammatory areas of colorectal tumours. ⺠12(S)-HETE and 12(S)-LOX over-expression stimulate malignant growth and migration. ⺠12(S)-LOX over-expressing SW480 cells have a higher tendency to metastasise. ⺠Blocking 12(S)-LOX activity or expression inhibits malignant growth and migration.
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Authors
T. Klampfl, E. Bogner, W. Bednar, L. Mager, D. Massudom, I. Kalny, C. Heinzle, W. Berger, S. Stättner, J. Karner, M. Klimpfinger, G. Fürstenberger, P. Krieg, B. Marian,