| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10904462 | Experimental Cell Research | 2012 | 13 Pages |
Abstract
Our data demonstrate that L-PGDS is a novel pro-adipogenic factor in human MSCs which might be of relevance in adipocyte metabolism and disease. L-PGDS gene expression is a potential quality marker for human MSCs, as it might predict unwanted adipogenic differentiation after MSC transplantation.
Keywords
COXSterol regulatory element-binding transcription factor 1SREBP1CEBPαATP-binding cassette sub-family G member 1LXRαABCG1GLUT4TAF1FCSFABP4ABCA1PPARγMSCsGAPDHL-PGDScyclooxygenaseApoeapolipoprotein EAdipocyte differentiationfetal calf serumMesenchymal stromal cellsbone marrowPlatelet lysateCCAAT/enhancer binding protein alphafatty acid binding protein 4perilipinPLINPeroxisome proliferator-activated receptor gamma
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Authors
Claudia Lange, Bärbel Brunswig-Spickenheier, Leah Eissing, Ludger Scheja,