| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10904493 | Experimental Cell Research | 2012 | 9 Pages |
Abstract
⺠We report on a new 3-D spheroid cell culture system aimed to mimic solid tumors. ⺠The cells reproducibly formed spheroids in the NanoCulture® plates. ⺠Cells in spheroids showed properties reminiscent of hypoxic stem cells. ⺠Measurement of cytotoxicity was simplified, using fluorescence from GFP marked cells. ⺠This new 3-D system shows features of potential utility in cancer drug development.
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Authors
Henning Karlsson, MÃ¥rten Fryknäs, Rolf Larsson, Peter Nygren,