Article ID Journal Published Year Pages File Type
10904501 Experimental Cell Research 2011 11 Pages PDF
Abstract
► Proof-of-principle new screen for BRCA2 VUS characterization. ► BRCA2 linker region influences cisplatin-induced cell death. ► VUS modify effect of BRCA2 linker region on cell response to cisplatin treatment.
Keywords
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cancer Research
Preview
A new assay for functional screening of BRCA2 linker region mutations identifies variants that alter chemoresistance to cisplatin
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