Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10904647 | Experimental Cell Research | 2011 | 6 Pages |
Abstract
Chemokines are a superfamily of structurally homologous heparin-binding proteins that influence tumor growth and metastasis. Several members of the CXC and CC chemokine families are potent inducers of neovascularization, whereas a subset of the CXC chemokines are potent inhibitors. In this paper, we review the current literature regarding the role of chemokines as mediators of tumor angiogenesis and neovascularization.
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Authors
Ellen C. Keeley, Borna Mehrad, Robert M. Strieter,