| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10904665 | Experimental Cell Research | 2009 | 11 Pages |
Abstract
We conclude that FF deteriorates the actin cytoskeleton in Caco-2 leading to reduced protein sorting and hampered endocytic events with subsequent alterations in the protein and lipid composition of the BBM. The reduced levels of the disaccharidase SI in the BBM suggest a potential pathomechanism of carbohydrate malabsorption in CD.
Keywords
LPHDipeptidylpeptidase IVHBBmAbAPNBBMHRPDPPIVWGACytoDOVAPFABSAbovine serum albuminAminopeptidase NMonoclonal antibodyHuman leukocyte antigenHLAEndocytosisOvalbuminBrush border membraneCeliac diseaseSucrase-isomaltaseactin cytoskeletoncytochalasin DProtein traffickingLactase-phlorizin hydrolaseparaformaldehydehorse radish peroxidaseWheat germ agglutinin
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Authors
Yvonne Reinke, Klaus-Peter Zimmer, Hassan Y. Naim,