Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10907424 | Experimental Hematology | 2010 | 12 Pages |
Abstract
These data show that glutamate release from megakaryocytes occurs in a SNARE-dependent, exocytotic manner and is increased during differentiation, suggesting that manipulation of glutamate signaling could influence megakaryocytopoiesis and, therefore, offer a suitable target for the treatment of thrombosis and other hematological disorders.
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Authors
Catherine J. Thompson, Tatjana Schilling, Martin R. Howard, Paul G. Genever,