| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10907463 | Experimental Hematology | 2009 | 31 Pages |
Abstract
We demonstrated that WEB-2170 is a powerful antileukemic agent with interesting translational opportunities to treat AML and described mechanisms of drug-induced intrinsic and extrinsic apoptosis both in AML cell lines and blasts from AML patients by addressing PTEN as the master regulator of the whole process.
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Authors
Cristina Cellai, Anna Laurenzana, Elisa Bianchi, Sara Sdelci, Rossella Manfredini, Alessandro M. Vannucchi, Roberto Caporale, Manjola Balliu, Francesco Mannelli, Sergio Ferrari, Alberto Bosi, Debora Miniati, Pier L. Cocco, Steeve Veronneau,