| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10907482 | Experimental Hematology | 2008 | 10 Pages |
Abstract
PTH induces mobilization of progenitor cells effectively, which can be related to an endogenous release of G-CSF. In contrast to G-CSF treatment, PTH does not result in a depletion of bone marrow, which may be mediated by an activation of PTH receptor on osteoblasts. The novel function of PTH on mobilization and regeneration of BMCs may pave the way for new therapeutic options in bone marrow and stem cell transplantation as well as in the field of ischemic disorders.
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Authors
Stefan Brunner, Marc-Michael Zaruba, Bruno Huber, Robert David, Marcus Vallaster, Gerald Assmann, Josef Mueller-Hoecker, Wolfgang-Michael Franz,