| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10907695 | Experimental Hematology | 2005 | 9 Pages |
Abstract
Weaker signals for Crk and Daxx may participate in less megakaryocyte suppressive activity of IFN-ζ/limitin and may distinguish IFN-ζ/limitin from IFN-α in megakaryocytes. Our results extend the understanding about thrombocytopenia in patients with IFN-α treatment as well as the possibility for the clinical application of human homologue of IFN-ζ/limitin or an engineered cytokine with useful features of the IFN-ζ/limitin structure.
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Authors
Naoko Ishida, Kenji Oritani, Masamichi Shiraga, Hitoshi Yoshida, Sin-ichiro Kawamoto, Hidetoshi Ujiie, Hiroaki Masaie, Michiko Ichii, Yoshiaki Tomiyama, Yuzuru Kanakura,