Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10907722 | Experimental Hematology | 2005 | 6 Pages |
Abstract
We demonstrate the ability of ER-retained IL-2 to provide autocrine growth stimulation to NK-92 cells, without secretion of the cytokine to the extracellular compartment. Therapy with IL-2 gene-modified autoactivating NK cells may avoid side effects imposed by exogenously administered IL-2.
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Authors
Kyriakos V. Konstantinidis, Evren Alici, Alar Aints, Birger Christensson, Hans-Gustaf Ljunggren, M. Sirac Dilber,