Article ID Journal Published Year Pages File Type
10907722 Experimental Hematology 2005 6 Pages PDF
Abstract
We demonstrate the ability of ER-retained IL-2 to provide autocrine growth stimulation to NK-92 cells, without secretion of the cytokine to the extracellular compartment. Therapy with IL-2 gene-modified autoactivating NK cells may avoid side effects imposed by exogenously administered IL-2.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cancer Research
Authors
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