Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10907769 | Experimental Hematology | 2005 | 7 Pages |
Abstract
Hydroxamic acid derivatives can stimulate the in vivo erythropoiesis and fetal globin production in a thalassemic murine model. The combined effect of certain histone deacetylase inhibitors on erythropoiesis and on γ gene expression make these compounds desirable targets for development of therapeutics for β chain hemoglobinopathies.
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Authors
Hua Cao, Manfred Jung, George Stamatoyannopoulos,