| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10907776 | Experimental Hematology | 2005 | 8 Pages |
Abstract
The high expression of CD27 and CD70 on ALL cells may represent an amplification of the normal CD27-CD70 expression present on early B cell progenitors. Our finding suggests that interference with CD27-CD70 interaction may represent novel treatment opportunities in ALL. Further studies are required to pin-point the role of this receptor-ligand pair in normal and malignant hematopoiesis.
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Authors
Anna Nilsson, Angelo de Milito, Frida Mowafi, Gösta Winberg, Olle Björk, Elisabeth Z. Wolpert, Francesca Chiodi,