Article ID Journal Published Year Pages File Type
10907827 Experimental Hematology 2005 11 Pages PDF
Abstract
1) HSP27 inhibits VP-16-mediated phosphorylation of p38 and c-Jun, cytochrome c release, and subsequent apoptosis; 2) HSP27 is expressed and activated in monocytic AML blasts; 3) cytoplasmic expression of p21 compensates for the lack of HSP27.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cancer Research
Authors
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