Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10907827 | Experimental Hematology | 2005 | 11 Pages |
Abstract
1) HSP27 inhibits VP-16-mediated phosphorylation of p38 and c-Jun, cytochrome c release, and subsequent apoptosis; 2) HSP27 is expressed and activated in monocytic AML blasts; 3) cytoplasmic expression of p21 compensates for the lack of HSP27.
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Authors
Hein Schepers, Marjan Geugien, Marco van der Toorn, Anton L. Bryantsev, Harm H. Kampinga, Bart J.L. Eggen, Edo Vellenga,