| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10907829 | Experimental Hematology | 2005 | 7 Pages |
Abstract
These findings show the role of PI3K in KITAsn822Lys-mediated constitutive activation through the Akt-independent downstream signaling pathway of JNK, and also demonstrate the mutant's susceptibility to STI 571, which may therefore have therapeutic potential in CBFL patients with susceptible KIT mutations.
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Authors
Alessandro Beghini, Melissa Bellini, Ivana Magnani, Patrizia Colapietro, Roberto Cairoli, Enrica Morra, Lidia Larizza,