Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10907890 | Experimental Hematology | 2005 | 13 Pages |
Abstract
These studies indicate that CTCE-0021 is an efficient and rapid mobilizer of PMN and HPC when used alone and shows synergistic activity when used in combination with G-CSF. The mobilizing effect of this peptide appears to be mediated by downregulation of the CXCR4 receptor on HPC and altered chemokine gradient.
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Authors
Louis M. Pelus, Huimin Bian, Seiji Fukuda, Donald Wong, Ahmed Merzouk, Hassan Salari,