Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10907907 | Experimental Hematology | 2005 | 8 Pages |
Abstract
Taken altogether, our data demonstrate that PKC-δ plays a critical role in Type I IFN signaling in BCR-ABL expressing cells, acting as a serine kinase for Stat1, to regulate transcriptional activation of interferon-regulated genes and induction of antileukemic responses.
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Authors
Surinder Kaur, Simrit Parmar, Jessica Smith, Efstratios Katsoulidis, Yongzhong Li, Antonella Sassano, Beata Majchrzak, Shahab Uddin, Martin S. Tallman, Eleanor N. Fish, Leonidas C. Platanias,