| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10908024 | Experimental Hematology | 2005 | 11 Pages |
Abstract
TGF-β1 may contribute to mast cell homeostasis by inhibiting maturation from bone marrow precursors. The effects of TGF-β1 result in greatly diminished expression of cell surface markers, reduced granulation, and lack of responsiveness to IgE-mediated activation. Thus TGF-β1 can serve as a potent and multifunctional regulator of mast cell maturation.
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Authors
Mohit Kashyap, Daniel P. Bailey, Gregorio Gomez, Juan Rivera, Thomas F. Huff, John J. Ryan,