Article ID Journal Published Year Pages File Type
10908744 Leukemia Research 2015 10 Pages PDF
Abstract

- Liposomes with TRAIL show greater cytotoxicity than soluble TRAIL in leukemic cells.
- Liposomes with TRAIL induce a more efficient clustering of DR5 which is responsible for their higher activity.
- Liposomes with TRAIL induce a more potent DISC recruitment than soluble TRAIL.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cancer Research
Authors
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