Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10908744 | Leukemia Research | 2015 | 10 Pages |
Abstract
- Liposomes with TRAIL show greater cytotoxicity than soluble TRAIL in leukemic cells.
- Liposomes with TRAIL induce a more efficient clustering of DR5 which is responsible for their higher activity.
- Liposomes with TRAIL induce a more potent DISC recruitment than soluble TRAIL.
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Authors
Diego De Miguel, Ana Gallego-Lleyda, Alberto Anel, Luis Martinez-Lostao,