| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10908848 | Leukemia Research | 2014 | 27 Pages |
Abstract
Flowcytometry analysis was carried out to evaluate the expression of the p-Stat3 in 50 CML patients and 20 age-matched healthy controls. p-Stat3 expression was increased in advanced stages of CML. Imatinib treatment was found to suppress the expression of p-Stat3 in bone marrow cells. The level of p-Stat3 was found to be higher in resistant cases than in responsive cases, which suggest the beneficial use of p-Stat3 as an indicator to follow the clinical course and the treatment response.
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Authors
Douaa Sayed, Hosny Badrawy, Noha Gaber, Muhammed R. Khalaf,