Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10909269 | Leukemia Research | 2012 | 6 Pages |
Abstract
Recently, according to the Hypereosinophilic Diseases Working Group of the International Eosinophil Society, six variants of hypereosinophilic syndrome have been proposed, i.e. (1) myeloproliferative, (2) lymphoproliferative, (3) idiopathic/undefined, (4) overlapping, (5) associated and (6) familial variant. Hypereosinophilic syndrome is a rare disorder in children and can occur at any age during childhood. Corticosteroids are the treatment of choice, whereas other treatment options are hydroxyurea, IFNα, imatinib, vincristine, mepolizumab. We present a fulminant fatal case of hypereosinophilic syndrome in a teenager with an initial presentation of an idiopathic thrombocytopenia (ITP) and present a narrative review of literature.
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Authors
M. van Grotel, M. de Hoog, R.R. de Krijger, H.B. Beverloo, M.M. van den Heuvel-Eibrink,