Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10909429 | Leukemia Research | 2011 | 8 Pages |
Abstract
Taken together, TP53-independent up-regulation of p21waf1 activates caspase 3 and down-regulates Mcl-1 in AML cells. Combination of 5-AzadC and MS-275 may be a promising treatment strategy for individuals with leukemia in which TP53 is inactivated.
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Authors
Chie Nishioka, Takayuki Ikezoe, Jing Yang, Keiko Udaka, Akihito Yokoyama,