Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10910825 | Lung Cancer | 2015 | 7 Pages |
Abstract
Evaluation of SNPs in CYP3A5 and CYP2D6 can effectively predict severe hepatotoxicity induced by gefitinib. Erlotinib can be used as an alternative treatment for patients who develop gefitinib-induced severe hepatotoxicity.
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Authors
Eri Sugiyama, Shigeki Umemura, Shogo Nomura, Keisuke Kirita, Shingo Matsumoto, Kiyotaka Yoh, Seiji Niho, Hironobu Ohmatsu, Masahiro Tsuboi, Yuichiro Ohe, Koichi Goto,