| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10910834 | Lung Cancer | 2015 | 5 Pages |
Abstract
This case highlights acquisition of EGFR-TKI resistance by transformation to LCNEC, not SCLC. Loss of EGFR and Rb expression in the LCNEC suggests the same mechanism as transformation to SCLC. Further study is needed to elucidate this mechanism, especially regarding the similarities and differences to SCLC.
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Cancer Research
Authors
Mariko Kogo, Ryoko Shimizu, Keiichiro Uehara, Yutaka Takahashi, Masaki Kokubo, Yukihiro Imai, Keisuke Tomii,