Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10911210 | Lung Cancer | 2014 | 7 Pages |
Abstract
Our findings argue for an enrichment of FGFR1 amplifications in brain metastases of adenocarcinomas (where they were 5-fold more frequent than reported for primary tumors) and possibly also of other non-squamous carcinomas, but not in squamous cell carcinomas of the lung. These results may be relevant for targeted therapy and prophylaxis of NSCLC brain metastases.
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Authors
Matthias Preusser, Anna S. Berghoff, Walter Berger, Aysegül Ilhan-Mutlu, Carina Dinhof, Georg Widhalm, Karin Dieckmann, Adelheid Wöhrer, Monika Hackl, Andreas von Deimling, Berthold Streubel, Peter Birner,