Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10911264 | Lung Cancer | 2012 | 6 Pages |
Abstract
Though we found that EGFR WT/KRAS mutant advanced NSCLC patients are associated with an increased resistance to treatment, specific mutant KRAS may account for differential sensitivity to an EGFR-TKI. KRAS codon 13 mutants are those who seem to experience the worse clinical outcome.
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Authors
Giulio Metro, Rita Chiari, Simona Duranti, Annamaria Siggillino, Matthias J. Fischer, Diana Giannarelli, Vienna Ludovini, Chiara Bennati, Luca Marcomigni, Alice Baldi, Michele Giansanti, Vincenzo Minotti, Lucio Crinò,